01 -
Preheat oven to 375°F. Line a rimmed baking sheet with aluminum foil or parchment paper.
02 -
Pat the pork loin dry using paper towels to remove surface moisture.
03 -
Combine paprika, garlic powder, onion powder, thyme, rosemary, salt, and black pepper in a small bowl.
04 -
Lightly spray the pork loin with a neutral cooking spray and evenly coat with the prepared spice blend.
05 -
Heat 1 tablespoon olive oil in a large skillet over medium heat. Sear the pork loin until browned on all sides, about 3 to 5 minutes per side.
06 -
Place the seared pork loin, fat side up, on the prepared baking sheet.
07 -
Whisk together minced garlic, honey, soy sauce, Dijon mustard, and 1 tablespoon olive oil in a bowl until smooth. Adjust consistency by adding additional oil or soy sauce if needed. Reserve 2 tablespoons of the glaze for the vegetables.
08 -
Brush the pork loin with the remaining honey soy glaze.
09 -
Roast the pork loin for 25 minutes.
10 -
Toss Brussels sprouts and butternut squash with 1 tablespoon olive oil and the reserved honey soy glaze in a large mixing bowl.
11 -
Arrange the glazed vegetables around the pork loin on the baking sheet.
12 -
Lightly tent the baking sheet with aluminum foil to shield from over-browning.
13 -
Continue roasting for an additional 25 to 30 minutes, stirring vegetables halfway, until an instant-read thermometer inserted into the thickest part of the pork registers 145°F.
14 -
Remove from the oven and loosely cover the pork loin with foil. Allow to rest for 10 minutes before carving.
15 -
Slice the pork loin and serve alongside roasted Brussels sprouts and butternut squash.